PMID: 18691054

Zhou SF, Wang LL, Di YM, Xue CC, Duan W, Li CG, Li Y
Substrates and inhibitors of human multidrug resistance associated proteins and the implications in drug development.
Curr Med Chem. 2008;15(20):1981-2039., [PubMed]
Sentences
No. Mutations Sentence Comment
568 ABCC1 p.Glu1089Gln
X
ABCC1 p.Glu1089Gln 18691054:568:201
status: NEW
view ABCC1 p.Glu1089Gln details
 More NH2-proximal regions of TMD2 also appear to be involved in LY475776 binding since tryptic fragments corresponding to TM12/13 and TM14/15 are photolabeled, and photolabeling is reduced in the TM14 Glu1089Gln MRP1/ABCC1 mutant [252,253]. Login to comment