PMID: 18377430

Lal S, Wong ZW, Sandanaraj E, Xiang X, Ang PC, Lee EJ, Chowbay B
Influence of ABCB1 and ABCG2 polymorphisms on doxorubicin disposition in Asian breast cancer patients.
Cancer Sci. 2008 Apr;99(4):816-23., [PubMed]
Sentences
No. Mutations Sentence Comment
161 ABCC1 p.Arg433Ser
X
ABCC1 p.Arg433Ser 18377430:161:51
status: NEW
view ABCC1 p.Arg433Ser details
 (44) Naturally occurring non-synonymous mutations (Arg433Ser) in the MRP1 cytoplasmic domain, leading to doxorubicin resistance,(45) also needs further investigation in terms of its role in altering doxorubicin disposition in cancer patients. Login to comment