PMID: 18230051

Hahnen E, Hauke J, Trankle C, Eyupoglu IY, Wirth B, Blumcke I
Histone deacetylase inhibitors: possible implications for neurodegenerative disorders.
Expert Opin Investig Drugs. 2008 Feb;17(2):169-84., [PubMed]
Sentences
No. Mutations Sentence Comment
280 ABCD2 p.Ala30Pro
X
ABCD2 p.Ala30Pro 18230051:280:148
status: NEW
view ABCD2 p.Ala30Pro details
 Even though no direct binding of α-synuclein to histone acetyltransferases was found, wild-type as well as mutant α-synuclein proteins (A30P, A53T) inhibit histone acetylation mediated by CBP, p300 and P/CAF in vitro. Login to comment