PMID: 18195111

May K, Minarikova V, Linnemann K, Zygmunt M, Kroemer HK, Fusch C, Siegmund W
Role of the multidrug transporter proteins ABCB1 and ABCC2 in the diaplacental transport of talinolol in the term human placenta.
Drug Metab Dispos. 2008 Apr;36(4):740-4. Epub 2008 Jan 14., [PubMed]
Sentences
No. Mutations Sentence Comment
126 ABCB1 p.Gly1249Ala
X
ABCB1 p.Gly1249Ala 18195111:126:99
status: NEW
view ABCB1 p.Gly1249Ala details
 There is evidence from literature that the genetic polymorphisms ABCB1 G2677T and C3435T and ABCC2 G1249A are associated with altered expression of the transporters in the human placenta (Hitzl et al., 2004; Meyer zu Schwabedissen et al., 2005). Login to comment