PMID: 18004213

Alfirevic A, Mills T, Carr D, Barratt BJ, Jawaid A, Sherwood J, Smith JC, Tugwood J, Hartkoorn R, Owen A, Park KB, Pirmohamed M
Tacrine-induced liver damage: an analysis of 19 candidate genes.
Pharmacogenet Genomics. 2007 Dec;17(12):1091-100., [PubMed]
Sentences
No. Mutations Sentence Comment
196 ABCB4 p.Leu1082Gln
X
ABCB4 p.Leu1082Gln 18004213:196:40
status: NEW
view ABCB4 p.Leu1082Gln details
ABCB4 p.Ile764Leu
X
ABCB4 p.Ile764Leu 18004213:196:30
status: NEW
view ABCB4 p.Ile764Leu details
 Two ABCB4 nonsynonymous SNPs (I764L and L1082Q) were specific for drug-induced cholestasis and hepatocellular injury, respectively. Login to comment