PMID: 17960347

Nichols D, Chmiel J, Berger M
Chronic inflammation in the cystic fibrosis lung: alterations in inter- and intracellular signaling.
Clin Rev Allergy Immunol. 2008 Apr;34(2):146-62., [PubMed]
Sentences
No. Mutations Sentence Comment
300 ABCC7 p.Gly551Asp
X
ABCC7 p.Gly551Asp 17960347:300:12
status: NEW
view ABCC7 p.Gly551Asp details
 Studies in (G551D) cftr-/- mice in which normal human CFTR was selectively expressed in particular cell types 154 using transgenes with tissue-specific promoters suggested that defective CFTR function in the epithelium was necessary and sufficient to cause characteristic abnormalities in the response to LPS in the lung [136]. Login to comment