ABCMdb

PMID: 17766193

Bangel N, Dahlhoff C, Sobczak K, Weber WM, Kusche-Vihrog K
Upregulated expression of ENaC in human CF nasal epithelium.
J Cyst Fibros. 2008 May;7(3):197-205. Epub 2007 Sep 4., [PubMed]

Sentences

No. Mutations Sentence Comment

55 ABCC7 p.Arg553* For qRT-PCR experiments we analysed five patients homozygous for ΔF508 and one with a compound heterozygoty for ΔF508/R553X (also used for molecular cloning). Login to comment 56 ABCC7 p.Arg553* For qRT-PCR experiments we analysed five patients homozygous for ƊF508 and one with a compound heterozygoty for ƊF508/R553X (also used for molecular cloning). Login to comment 164 ABCC7 p.Thr663Ala We found a similar situation for Table 2 Single nucleotide polymorphisms in the α-, β- and γ-hnENaC subunits from CF and non-CF tissue and appropriate references α-ENaC Reference β-ENaC Reference γ-ENaC Reference T663A [53,54] A314G [55] R178W P502A A614S [53,55,56] A336P [53,56] F339S A350T Y369S D375G S458R [55] Fig. 2. mRNA expression data for all three hnENaC subunits of CF patients. Login to comment 170 ABCC7 p.Thr663Ala We found a similar situation for Table 2 Single nucleotide polymorphisms in the b1;-, b2;- and b3;-hnENaC subunits from CF and non-CF tissue and appropriate references b1;-ENaC Reference b2;-ENaC Reference b3;-ENaC Reference T663A [53,54] A314G [55] R178W P502A A614S [53,55,56] A336P [53,56] F339S A350T Y369S D375G S458R [55] Fig. 2. Login to comment 214 ABCC7 p.Thr663Ala We identified a common T663A polymorphism within the C-terminus of the hnENaC α-subunit of CF and non-CF epithelia. Login to comment 221 ABCC7 p.Thr663Ala We identified a common T663A polymorphism within the C-terminus of the hnENaC b1;-subunit of CF and non-CF epithelia. Login to comment