PMID: 17597712

Kiser JJ, Carten ML, Aquilante CL, Anderson PL, Wolfe P, King TM, Delahunty T, Bushman LR, Fletcher CV
The effect of lopinavir/ritonavir on the renal clearance of tenofovir in HIV-infected patients.
Clin Pharmacol Ther. 2008 Feb;83(2):265-72. Epub 2007 Jun 27., [PubMed]
Sentences
No. Mutations Sentence Comment
201 ABCC2 p.Val417Ile
X
ABCC2 p.Val417Ile 17597712:201:8
status: NEW
view ABCC2 p.Val417Ile details
 G1249A (Val417Ile) Exon 10 23.3% CA 23.9% AA In membrane spanning domain, could alter substrate specificity (Ito, S. et al. Pharmacogenetics 11:175-184 (2001); Toh, S. et al. Am. J. Hum. Login to comment