PMID: 17569216

Limtrakul P
Curcumin as chemosensitizer.
Adv Exp Med Biol. 2007;595:269-300., [PubMed]
Sentences
No. Mutations Sentence Comment
82 ABCG2 p.Asn557Asp
X
ABCG2 p.Asn557Asp 17569216:82:62
status: VERIFIED
view ABCG2 p.Asn557Asp details
ABCG2 p.Asn557Asp
X
ABCG2 p.Asn557Asp 17569216:82:98
status: VERIFIED
view ABCG2 p.Asn557Asp details
 Cells transfected with mutant ABCG2 cDNA with substitution of Asn residue at position 557 to Asp (N557D) exhibited comparable resistance to mitoxantrone but significantly reduced resistance to SN-38 relative to wild-type protein. Position 557 is predicted to be located within or proximal to the TM5 segment. Login to comment