PMID: 17417653

Kamada K, Kubota Y, Arata T, Shindo Y, Hanaoka F
Structure of the human GINS complex and its assembly and functional interface in replication initiation.
Nat Struct Mol Biol. 2007 May;14(5):388-96. Epub 2007 Apr 8., [PubMed]
Sentences
No. Mutations Sentence Comment
151 ABCB3 p.Ser145Ala
X
ABCB3 p.Ser145Ala 17417653:151:541
status: NEW
view ABCB3 p.Ser145Ala details
 (d) Chromatin-bound fractions in Xenopus GINS extracts immunodepleted by Xenopus Psf2 antibody, without sperm (lane 1) and with sperm (lanes 2-10), supplemented with 0.76 mM recombinant human GINS complex (lanes 1 and 2) or one of the following mutant complexes: domain deletion mutant GINS1Dc2 (lane 3) or GINS5Dc (lane 4); site-directed mutant GINS1Y147A (lane 5) or GINS1F176A (lane 6); or linker mutant GINS1-1 (L134A D135A I136A; lane 7), GINS1-2 (T137A Q138A D139A; lane 8), GINS1-3 (M140A K141A P142A; lane 9) or GINS1-4 (P143A K144A S145A; lane 10). Login to comment