PMID: 17272824

Saadane A, Masters S, DiDonato J, Li J, Berger M
Parthenolide inhibits IkappaB kinase, NF-kappaB activation, and inflammatory response in cystic fibrosis cells and mice.
Am J Respir Cell Mol Biol. 2007 Jun;36(6):728-36. Epub 2007 Feb 1., [PubMed]
Sentences
No. Mutations Sentence Comment
61 ABCC7 p.Ser489*
X
ABCC7 p.Ser489* 17272824:61:63
status: NEW
view ABCC7 p.Ser489* details
 These are stock CftrtmtUnc -TgN(FABPCFTR)#Jaw mice bearing the S489X mutation in cftr and also a transgene for full-length human CFTR driven by the fatty acid-binding promoter (FABP), which restores CFTR function in the intestinal tract. Login to comment