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PMID: 17108809
Schaefer M, Roots I, Gerloff T
In-vitro transport characteristics discriminate wild-type ABCB1 (MDR1) from ALA893SER and ALA893THR polymorphisms.
Pharmacogenet Genomics. 2006 Dec;16(12):855-61.,
[PubMed]
Sentences
No.
Mutations
Sentence
Comment
41
ABCB1 p.Pro1028Gln
X
ABCB1 p.Pro1028Gln 17108809:41:143
status:
NEW
view ABCB1 p.Pro1028Gln details
Therefore, point mutations were introduced at divergent cDNA positions in the ABCB1 wild-type [G1236T (Gly412Gly), C1727T (Ala579Val), C3083A (
Pro1028Gln
)] by site-directed mutagenesis, using the QuikChange Site-Directed Mutagenesis Kit (Stratagene) and specific mismatch primers (MWG, Ebersberg, Germany).
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