PMID: 17108809

Schaefer M, Roots I, Gerloff T
In-vitro transport characteristics discriminate wild-type ABCB1 (MDR1) from ALA893SER and ALA893THR polymorphisms.
Pharmacogenet Genomics. 2006 Dec;16(12):855-61., [PubMed]
Sentences
No. Mutations Sentence Comment
41 ABCB1 p.Pro1028Gln
X
ABCB1 p.Pro1028Gln 17108809:41:143
status: NEW
view ABCB1 p.Pro1028Gln details
Therefore, point mutations were introduced at divergent cDNA positions in the ABCB1 wild-type [G1236T (Gly412Gly), C1727T (Ala579Val), C3083A (Pro1028Gln)] by site-directed mutagenesis, using the QuikChange Site-Directed Mutagenesis Kit (Stratagene) and specific mismatch primers (MWG, Ebersberg, Germany). Login to comment