PMID: 16691490

Loo TW, Bartlett MC, Clarke DM
Rescue of folding defects in ABC transporters using pharmacological chaperones.
J Bioenerg Biomembr. 2005 Dec;37(6):501-7., [PubMed]
Sentences
No. Mutations Sentence Comment
76 ABCB1 p.Gly268Val
X
ABCB1 p.Gly268Val 16691490:76:71
status: NEW
view ABCB1 p.Gly268Val details
ABCB1 p.Ala841Leu
X
ABCB1 p.Ala841Leu 16691490:76:92
status: NEW
view ABCB1 p.Ala841Leu details
 The presence of a processing mutation in either half-molecule (N-half (G268V) or COOH-half (A841L)) resulted in the loss of interactions between the half-molecules. Login to comment