PMID: 16691488

Al-Shawi MK, Omote H
The remarkable transport mechanism of P-glycoprotein: a multidrug transporter.
J Bioenerg Biomembr. 2005 Dec;37(6):489-96., [PubMed]
Sentences
No. Mutations Sentence Comment
137 ABCB1 p.Gly185Val
X
ABCB1 p.Gly185Val 16691488:137:13
status: NEW
view ABCB1 p.Gly185Val details
 The mutation G185V increases the strength of colchicine and etoposide interaction with the transition state and improves the transport of these drugs by reducing the level of failed transport (Omote et al., 2004). Login to comment