PMID: 16209890

Takano M, Yumoto R, Murakami T
Expression and function of efflux drug transporters in the intestine.
Pharmacol Ther. 2006 Jan;109(1-2):137-61. Epub 2005 Oct 4., [PubMed]
Sentences
No. Mutations Sentence Comment
1100 ABCC1 p.Ala893Ser
X
ABCC1 p.Ala893Ser 16209890:1100:110
status: NEW
view ABCC1 p.Ala893Ser details
 Siegmund et al. (2002b) investigated the influence of the hereditary variants C3435T in exon 26 and G2677T/A (Ala893Ser/Thr) in exon 21, as well as the influence of 7 frequent or putative functional single nucleotide polymorphisms (SNPs) on duodenum MDR1 mRNA and P-gp expression and on talinolol disposition after intravenous and oral administration. Login to comment