ABCMdb

PMID: 16177360

Reiniger N, Ichikawa JK, Pier GB
Influence of cystic fibrosis transmembrane conductance regulator on gene expression in response to Pseudomonas aeruginosa infection of human bronchial epithelial cells.
Infect Immun. 2005 Oct;73(10):6822-30., [PubMed]

Sentences

No. Mutations Sentence Comment

42 ABCC7 p.Trp1282* IB3-1 (CF-IB3-1) and S9 (WT CFTR S9) are both human bronchial epithelial cell lines with the compound heterozygous background of ⌬F508/ W1282X alleles of CFTR (12). Login to comment 138 ABCC7 p.Trp1282* Cell lysates from WT CFTR S9 and CF- IB3-1 (⌬F508/W1282X CFTR) cells both uninfected and infected with P. aeruginosa strain PAO1 for 3 h were assayed to determine their levels of IL-6, IL-8, CXCL1, and ICAM-1. Login to comment 233 ABCC7 p.Trp1282* Aminoglycosides are known to cause read-through of stop mutations, such as the W1282X mutation present in CF-IB3-1 cells (4, 18). Login to comment