PMID: 16166320

Shafran A, Ifergan I, Bram E, Jansen G, Kathmann I, Peters GJ, Robey RW, Bates SE, Assaraf YG
ABCG2 harboring the Gly482 mutation confers high-level resistance to various hydrophilic antifolates.
Cancer Res. 2005 Sep 15;65(18):8414-22., 2005-09-15 [PubMed]
Sentences
No. Mutations Sentence Comment
22 ABCG2 p.Arg482Ser
X
ABCG2 p.Arg482Ser 16166320:22:100
status: VERIFIED
view ABCG2 p.Arg482Ser details
ABCG2 p.Arg482Met
X
ABCG2 p.Arg482Met 16166320:22:90
status: VERIFIED
view ABCG2 p.Arg482Met details
 Sequencing of the Abcg2 gene in these drug-resistant cell lines identified two mutations, R482M and R482S. Login to comment