PMID: 16105987

Wu P, Oleschuk CJ, Mao Q, Keller BO, Deeley RG, Cole SP
Analysis of human multidrug resistance protein 1 (ABCC1) by matrix-assisted laser desorption ionization/time of flight mass spectrometry: toward identification of leukotriene C4 binding sites.
Mol Pharmacol. 2005 Nov;68(5):1455-65. Epub 2005 Aug 16., [PubMed]
Sentences
No. Mutations Sentence Comment
262 ABCC1 p.Tyr1243Phe
X
ABCC1 p.Tyr1243Phe 16105987:262:26
status: NEW
view ABCC1 p.Tyr1243Phe details
 Likewise, substitution of Tyr1243 with Phe causes a 70% reduction in 17beta-estradiol-D-17beta-glucuronide transport but has little effect on LTC4 transport (Zhang et al., 2002). Login to comment