PMID: 16085675

Farmen SL, Karp PH, Ng P, Palmer DJ, Koehler DR, Hu J, Beaudet AL, Zabner J, Welsh MJ
Gene transfer of CFTR to airway epithelia: low levels of expression are sufficient to correct Cl- transport and overexpression can generate basolateral CFTR.
Am J Physiol Lung Cell Mol Physiol. 2005 Dec;289(6):L1123-30. Epub 2005 Aug 5., [PubMed]
Sentences
No. Mutations Sentence Comment
272 ABCC7 p.Ser1455*
X
ABCC7 p.Ser1455* 16085675:272:112
status: NEW
view ABCC7 p.Ser1455* details
 Third, evidence that mislocalization of CFTR might have a physiological consequence comes from the study of the S1455X mutation, which was located in the basolateral membrane in airway epithelial cells (27). Login to comment 275 ABCC7 p.Ser1455*
X
ABCC7 p.Ser1455* 16085675:275:112
status: NEW
view ABCC7 p.Ser1455* details
 Third, evidence that mislocalization of CFTR might have a physiological consequence comes from the study of the S1455X mutation, which was located in the basolateral membrane in airway epithelial cells (27). Login to comment