PMID: 16084692

Tabary O, Boncoeur E, de Martin R, Pepperkok R, Clement A, Schultz C, Jacquot J
Calcium-dependent regulation of NF-(kappa)B activation in cystic fibrosis airway epithelial cells.
Cell Signal. 2006 May;18(5):652-60. Epub 2005 Aug 9., [PubMed]
Sentences
No. Mutations Sentence Comment
2 ABCC7 p.Trp1282*
X
ABCC7 p.Trp1282* 16084692:2:143
status: NEW
view ABCC7 p.Trp1282* details
 The hypothesis that Ca2+ signaling may regulate NF-nB activation was tested in a CF bronchial epithelial cell line (IB3-1, CFTR genotype DF508/W1282X) and compared to the CFTR-corrected epithelial cell line S9 using fluorescence microscopy to visualized in situ NF-nB activation at the single cell level. Login to comment 47 ABCC7 p.Trp1282*
X
ABCC7 p.Trp1282* 16084692:47:104
status: NEW
view ABCC7 p.Trp1282* details
 Cell lines and culture conditions The airway epithelial cell lines used were IB3-1 (CFTR genotype DF508/W1282X) and cells derived from IB3-1 that were stably transfected to achieve low-level expression of full-length wild-type CFTR (S9 cells). Login to comment