PMID: 15931768

Chowbay B, Zhou S, Lee EJ
An interethnic comparison of polymorphisms of the genes encoding drug-metabolizing enzymes and drug transporters: experience in Singapore.
Drug Metab Rev. 2005;37(2):327-78., [PubMed]
Sentences
No. Mutations Sentence Comment
427 ABCC1 p.Ala893Ser
X
ABCC1 p.Ala893Ser 15931768:427:245
status: NEW
view ABCC1 p.Ala893Ser details
 Kim et al. (2001) indicated that cells transduced with a variant MDR1 containing Ser893 showed reduced intracellular accumulation of [3 H]-digoxin compared with cells with the wild-type Ala893 , suggesting enhanced efflux by the polymorphism of Ala893Ser (G2677T). Login to comment