PMID: 15778422

Putnam WS, Woo JM, Huang Y, Benet LZ
Effect of the MDR1 C3435T variant and P-glycoprotein induction on dicloxacillin pharmacokinetics.
J Clin Pharmacol. 2005 Apr;45(4):411-21., [PubMed]
Sentences
No. Mutations Sentence Comment
121 ABCB1 p.Asn21Asp
X
ABCB1 p.Asn21Asp 15778422:121:191
status: NEW
view ABCB1 p.Asn21Asp details
 These results are consistent with the linkage reported between the 6 variant sites in the MDR1*13 haplotype.17 Three of the subjects in the 3435TT group also had a MDR1 variant leading to an Asn21Asp change in P-glycoprotein. Login to comment