PMID: 15574409

Shao B, Bergt C, Fu X, Green P, Voss JC, Oda MN, Oram JF, Heinecke JW
Tyrosine 192 in apolipoprotein A-I is the major site of nitration and chlorination by myeloperoxidase, but only chlorination markedly impairs ABCA1-dependent cholesterol transport.
J Biol Chem. 2005 Feb 18;280(7):5983-93. Epub 2004 Nov 30., [PubMed]
Sentences
No. Mutations Sentence Comment
159 ABCA1 p.Tyr115Cys
X
ABCA1 p.Tyr115Cys 15574409:159:46
status: NEW
view ABCA1 p.Tyr115Cys details
The apoA-I cysteine substitutions Y18C, Y29C, Y115C, Y166C, Y192C, and Y236C were bacterially expressed, purified, and labeled as described (50). Login to comment
160 ABCA1 p.Tyr115Cys
X
ABCA1 p.Tyr115Cys 15574409:160:46
status: NEW
view ABCA1 p.Tyr115Cys details
The apoA-I cysteine substitutions Y18C, Y29C, Y115C, Y166C, Y192C, and Y236C were bacterially expressed, purified, and labeled as described (50). Login to comment