PMID: 15464445

Davis PB, Drumm ML
Some like it hot: curcumin and CFTR.
Trends Mol Med. 2004 Oct;10(10):473-5., [PubMed]
Sentences
No. Mutations Sentence Comment
13 ABCC7 p.Trp1282*
X
ABCC7 p.Trp1282* 15464445:13:131
status: NEW
view ABCC7 p.Trp1282* details
ABCC7 p.Gly542*
X
ABCC7 p.Gly542* 15464445:13:139
status: NEW
view ABCC7 p.Gly542* details
 The best-studied therapy is gentamicin, which causes read-through of 'stop` codons and has been used to correct the defect for the W1282X, G542X and other similar CF mutations with some success in clinical trials [2]. Login to comment