PMID: 15351355

Galietta LJ, Moran O
Identification of CFTR activators and inhibitors: chance or design?
Curr Opin Pharmacol. 2004 Oct;4(5):497-503., [PubMed]
Sentences
No. Mutations Sentence Comment
31 ABCC7 p.Gly551Asp
X
ABCC7 p.Gly551Asp 15351355:31:26
status: NEW
view ABCC7 p.Gly551Asp details
ABCC7 p.Gly1349Asp
X
ABCC7 p.Gly1349Asp 15351355:31:36
status: NEW
view ABCC7 p.Gly1349Asp details
An example is provided by G551D and G1349D mutations, whose severe gating defect is partially corrected by the same openers - the flavonoids genistein and apigenin - that are effective on the F508del mutant [16-19]. Login to comment