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PMID: 15351355
Galietta LJ, Moran O
Identification of CFTR activators and inhibitors: chance or design?
Curr Opin Pharmacol. 2004 Oct;4(5):497-503.,
[PubMed]
Sentences
No.
Mutations
Sentence
Comment
31
ABCC7 p.Gly551Asp
X
ABCC7 p.Gly551Asp 15351355:31:26
status:
NEW
view ABCC7 p.Gly551Asp details
ABCC7 p.Gly1349Asp
X
ABCC7 p.Gly1349Asp 15351355:31:36
status:
NEW
view ABCC7 p.Gly1349Asp details
An example is provided by
G551D
and
G1349D
mutations, whose severe gating defect is partially corrected by the same openers - the flavonoids genistein and apigenin - that are effective on the F508del mutant [16-19].
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