PMID: 15007059

Zdebik AA, Cuffe JE, Bertog M, Korbmacher C, Jentsch TJ
Additional disruption of the ClC-2 Cl(-) channel does not exacerbate the cystic fibrosis phenotype of cystic fibrosis transmembrane conductance regulator mouse models.
J Biol Chem. 2004 May 21;279(21):22276-83. Epub 2004 Mar 7., 2004-05-21 [PubMed]
Sentences
No. Mutations Sentence Comment
57 ABCC7 p.Ser489*
X
ABCC7 p.Ser489* 15007059:57:237
status: NEW
view ABCC7 p.Ser489* details
 EXPERIMENTAL PROCEDURES Mice-ClC-2 knock-out mice, described previously (24) and backcrossed for seven generations into C57Bl6, were mated with heterozygous CFTR ⌬F508 mice (6) (CFTRkth , called Cftr⌬F/⌬F ) and CFTR S489X mice (5)(CFTRunc , called Cftr-/- ) (26) (both in C57Bl6 background) obtained from Jackson Laboratories. Login to comment