ABCMdb

PMID: 14764916

Bonora M, Bernaudin JF, Guernier C, Brahimi-Horn MC
Ventilatory responses to hypercapnia and hypoxia in conscious cystic fibrosis knockout mice Cftr-/-.
Pediatr Res. 2004 May;55(5):738-46. Epub 2004 Feb 5., [PubMed]

Sentences

No. Mutations Sentence Comment

27 ABCC7 p.Ser489* ABCC7 p.Ser489* Female and male 129/BC mice heterozygous for the S489X mutation were crossed to obtain homozygous S489X mice (7). Login to comment 33 ABCC7 p.Ser489* ABCC7 p.Ser489* Mice homozygous for the S489X mutation were classified as Cftr-/- , mice heterozygous for the S489X mutation as Cftrϩ/- , and wild-type mice as Cftrϩ/ϩ . Login to comment 149 ABCC7 p.Ser489* However, minor changes in the respiratory tract have been described in the models with the S489X Cftr mutation. Login to comment