PMID: 14551217

Al-Shawi MK, Polar MK, Omote H, Figler RA
Transition state analysis of the coupling of drug transport to ATP hydrolysis by P-glycoprotein.
J Biol Chem. 2003 Dec 26;278(52):52629-40. Epub 2003 Oct 9., 2003-12-26 [PubMed]
Sentences
No. Mutations Sentence Comment
359 ABCB1 p.Gly185Val
X
ABCB1 p.Gly185Val 14551217:359:42
status: NEW
view ABCB1 p.Gly185Val details
 Recently, we showed that the Pgp mutation G185V improves colchicine transport by enhancing its binding to the coupling transition state (62). Login to comment