PMID: 1322048

Anderson MP, Sheppard DN, Berger HA, Welsh MJ
Chloride channels in the apical membrane of normal and cystic fibrosis airway and intestinal epithelia.
Am J Physiol. 1992 Jul;263(1 Pt 1):L1-14., [PubMed]
Sentences
No. Mutations Sentence Comment
69 ABCC7 p.Arg347Glu
X
ABCC7 p.Arg347Glu 1322048:69:330
status: NEW
view ABCC7 p.Arg347Glu details
ABCC7 p.Lys335Glu
X
ABCC7 p.Lys335Glu 1322048:69:294
status: NEW
view ABCC7 p.Lys335Glu details
ABCC7 p.Lys95Asp
X
ABCC7 p.Lys95Asp 1322048:69:259
status: NEW
view ABCC7 p.Lys95Asp details
 Relative anion permeability of CAMP-regulated channels in apical membrane and in cells expressing wild-type and mutant CFTR PXlPCl- Gx/Gcl- Br- ClI- Br ClI- CAMP 3T3 fibroblasts CFTR 1.11 1.00 0.59 1.26 1.00 0.29 HeLa cells CFTR 1.24 1.00 0.57 1.02 1.00 0.39 K95D 1.25 1.00 1.43 1.39 1.00 0.75 K335E 1.06 1.00 1.37 1.71 1.00 1.43 R347E 1.24 1.00 0.90 1.46 1.00 0.47 Rl030E 1.46 1.00 0.81 1.50 1.00 0.28 Human airway epithelia Apical ND 1.00 0.41 ND 1.00 0.35 T84 epithelia Apical 1.21 1.00 0.56 0.92 1.00 0.47 over cations. Login to comment