PMID: 12867490

Nunoya K, Grant CE, Zhang D, Cole SP, Deeley RG
Molecular cloning and pharmacological characterization of rat multidrug resistance protein 1 (mrp1).
Drug Metab Dispos. 2003 Aug;31(8):1016-26., [PubMed]
Sentences
No. Mutations Sentence Comment
301 ABCC1 p.Glu1089Gln
X
ABCC1 p.Glu1089Gln 12867490:301:53
status: NEW
view ABCC1 p.Glu1089Gln details
ABCC1 p.Glu1089Lys
X
ABCC1 p.Glu1089Lys 12867490:301:64
status: NEW
view ABCC1 p.Glu1089Lys details
 Previously, we showed that the hMRP1 TM 14 mutations E1089Q and E1089K, which either reduce or completely eliminate resistance to doxorubicin and vincristine, had no effect on estrone 3-sulfate transport (Zhang et al., 2001b). Login to comment