PMID: 12729805

Sparreboom A, Danesi R, Ando Y, Chan J, Figg WD
Pharmacogenomics of ABC transporters and its role in cancer chemotherapy.
Drug Resist Updat. 2003 Apr;6(2):71-84., [PubMed]
Sentences
No. Mutations Sentence Comment
105 ABCC1 p.Ala893Ser
X
ABCC1 p.Ala893Ser 12729805:105:281
status: NEW
view ABCC1 p.Ala893Ser details
 One of the tested SNPs, the ABCB1 2677G>T/A (Mickley et al., 1998), contains a tri-allelic polymorphism (with G at nucleotide 2677 found in the wild-type sequence, and with A or T at that position being the two possible variants), which results in an amino acid change in exon 21 (Ala893Ser/Thr). Login to comment