PMID: 12704103

Darling KE, Evans TJ
Effects of nitric oxide on Pseudomonas aeruginosa infection of epithelial cells from a human respiratory cell line derived from a patient with cystic fibrosis.
Infect Immun. 2003 May;71(5):2341-9., [PubMed]
Sentences
No. Mutations Sentence Comment
278 ABCC7 p.Gly551Asp
X
ABCC7 p.Gly551Asp 12704103:278:74
status: NEW
view ABCC7 p.Gly551Asp details
ABCC7 p.Gly551Asp
X
ABCC7 p.Gly551Asp 12704103:278:75
status: NEW
view ABCC7 p.Gly551Asp details
 However, some patients with CF express a nonfunctional apical CFTR (e.g., G551D) that has the necessary domain to bind and internalize P. aeruginosa, and yet these patients have chronic colonization of the airways with P. aeruginosa as severe as that found in patients with no surface CFTR (e.g., ⌬F508) (52). Login to comment