PMID: 12594855

Garbi N, Tiwari N, Momburg F, Hammerling GJ
A major role for tapasin as a stabilizer of the TAP peptide transporter and consequences for MHC class I expression.
Eur J Immunol. 2003 Jan;33(1):264-73., [PubMed]
Sentences
No. Mutations Sentence Comment
164 ABCB3 p.Leu410Phe
X
ABCB3 p.Leu410Phe 12594855:164:138
status: NEW
view ABCB3 p.Leu410Phe details
 The interaction of tapasin with TAP appears to be mediated by the transmembrane (TM) region of tapasin, as suggested by a TM point mutant L410F of tapasin that fails to bind and stabilize TAP [4]. Login to comment