PMID: 12578988

Coleman FT, Mueschenborn S, Meluleni G, Ray C, Carey VJ, Vargas SO, Cannon CL, Ausubel FM, Pier GB
Hypersusceptibility of cystic fibrosis mice to chronic Pseudomonas aeruginosa oropharyngeal colonization and lung infection.
Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1949-54. Epub 2003 Feb 10., 2003-02-18 [PubMed]
Sentences
No. Mutations Sentence Comment
19 ABCC7 p.Ser489*
X
ABCC7 p.Ser489* 12578988:19:116
status: NEW
view ABCC7 p.Ser489* details
 Cftrtm1Unc -TgN(FABPCFTR) [fatty acid-binding protein (FABP)- CFTR] mice have a stop codon in the murine cftr gene (S489X) but also express human CFTR in the gut epithelium due to transgenic introduction of Cftr under the control of the FABP promoter (10). Login to comment