PMID: 12543662

Mann PA, Parmegiani RM, Wei SQ, Mendrick CA, Li X, Loebenberg D, DiDomenico B, Hare RS, Walker SS, McNicholas PM
Mutations in Aspergillus fumigatus resulting in reduced susceptibility to posaconazole appear to be restricted to a single amino acid in the cytochrome P450 14alpha-demethylase.
Antimicrob Agents Chemother. 2003 Feb;47(2):577-81., [PubMed]
Sentences
No. Mutations Sentence Comment
96 ABCB1 p.Gly54Trp
X
ABCB1 p.Gly54Trp 12543662:96:50
status: NEW
view ABCB1 p.Gly54Trp details
 In the mutant with a high level of POS resistance glycine 54 was mutated to tryptophan. Login to comment