PMID: 12464670

Ma T, Thiagarajah JR, Yang H, Sonawane ND, Folli C, Galietta LJ, Verkman AS
Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion.
J Clin Invest. 2002 Dec;110(11):1651-8., [PubMed]
Sentences
No. Mutations Sentence Comment
121 ABCC7 p.Gly551Asp
X
ABCC7 p.Gly551Asp 12464670:121:212
status: NEW
view ABCC7 p.Gly551Asp details
 Similar inhibitory potencies were found in cells that natively express wild-type CFTR, including T84 cells and primary cultures of human bronchial epithelial cells, as well as in transfected FRT cells expressing G551D-CFTR and ∆F508-CFTR (after low temperature correction) (not shown). Login to comment