PMID: 12397023

Gaden F, Franqueville L, Hong SS, Legrand V, Figarella C, Boulanger P
Mechanism of restriction of normal and cystic fibrosis transmembrane conductance regulator-deficient human tracheal gland cells to adenovirus infection and ad-mediated gene transfer.
Am J Respir Cell Mol Biol. 2002 Nov;27(5):628-40., [PubMed]
Sentences
No. Mutations Sentence Comment
268 ABCC8 p.Ser408Glu
X
ABCC8 p.Ser408Glu 12397023:268:53
status: NEW
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 A less pronounced cytotoxic effect was observed in a Ser-to-Glu substitution at position 408 (Table 1). Login to comment 272 ABCC8 p.Ser408Glu
X
ABCC8 p.Ser408Glu 12397023:272:247
status: NEW
view ABCC8 p.Ser408Glu details
 (A) Control, Ad5LacZ-FiWT carried WT fibers, whereas Ad5LacZ-FiK7 and Ad5LacZ-Fi408K7 carried a stretch of seven lysine residues (K7) in fusion to the C-terminus of the knob domain, and Ad5LacZ-Fi408K7 contained an additional fiber knob mutation (S408E). Login to comment