ABCMdb

PMID: 11960971

Freedman SD, Weinstein D, Blanco PG, Martinez-Clark P, Urman S, Zaman M, Morrow JD, Alvarez JG
Characterization of LPS-induced lung inflammation in cftr-/- mice and the effect of docosahexaenoic acid.
J Appl Physiol. 2002 May;92(5):2169-76., [PubMed]

Sentences

No. Mutations Sentence Comment

28 ABCC7 p.Ser489* To circumvent this problem, a model has been established whereby instillation of agarose beads coated with Pseudomonas into the lungs of S489X cftr-/- mice has been shown to result in increased inflammation and mortality compared with that observed in wild-type (WT) mice (13, 14). Login to comment 29 ABCC7 p.Ser489* To circumvent this problem, a model has been established whereby instillation of agarose beads coated with Pseudomonas into the lungs of S489X cftr-/- mice has been shown to result in increased inflammation and mortality compared with that observed in wild-type (WT) mice (13, 14). Login to comment 110 ABCC7 p.Gly551Asp Using a different approach, Thomas et al. (26a) have shown that intravenous administration of LPS leads to a qualitative increase in the number of neutrophils in the lung parenchyma of mice with the G551D mutation in CFTR compared Fig. 1. Login to comment 111 ABCC7 p.Gly551Asp Using a different approach, Thomas et al. (26a) have shown that intravenous administration of LPS leads to a qualitative increase in the number of neutrophils in the lung parenchyma of mice with the G551D mutation in CFTR compared Fig. 1. Login to comment