PMID: 11945068

Ziady AG, Kelley TJ, Milliken E, Ferkol T, Davis PB
Functional evidence of CFTR gene transfer in nasal epithelium of cystic fibrosis mice in vivo following luminal application of DNA complexes targeted to the serpin-enzyme complex receptor.
Mol Ther. 2002 Apr;5(4):413-9., [PubMed]
Sentences
No. Mutations Sentence Comment
172 ABCC7 p.Ser489*
X
ABCC7 p.Ser489* 11945068:172:66
status: NEW
view ABCC7 p.Ser489* details
ABCC7 p.Ser489*
X
ABCC7 p.Ser489* 11945068:172:67
status: NEW
view ABCC7 p.Ser489* details
 We studied 8to 10-week-old B6.129P2-cftrtm1Unc mice (CF knockout, S489X mice) [25] fed a liquid diet [26], or STOCK Cftrtm1Unc - TgN(FABPCFTR)#Jaw mice [27], which are CF mutant mice with the defect corrected only in intestinal epithelium by transgenic human CFTR. Login to comment