PMID: 11846560

Chaillan-Huntington C, Butler PJ, Huntington JA, Akin D, Feldherr C, Stewart M
NTF2 monomer-dimer equilibrium.
J Mol Biol. 2001 Nov 30;314(3):465-77., [PubMed]
Sentences
No. Mutations Sentence Comment
123 ABCB2 p.Val94Asp
X
ABCB2 p.Val94Asp 11846560:123:185
status: NEW
view ABCB2 p.Val94Asp details
 Although not always conserved as methionine, the residue corresponding to Met84 in vertebrate NTF2 is invariably hydrophobic in TAP1, Mex67 and NXT1, and mutations here (F465H in TAP1; V94D in NXT1) reduce heterodimer formation. Login to comment