PMID: 11823525

Soltys J, Bonfield T, Chmiel J, Berger M
Functional IL-10 deficiency in the lung of cystic fibrosis (cftr(-/-)) and IL-10 knockout mice causes increased expression and function of B7 costimulatory molecules on alveolar macrophages.
J Immunol. 2002 Feb 15;168(4):1903-10., 2002-02-15 [PubMed]
Sentences
No. Mutations Sentence Comment
43 ABCC7 p.Ser489*
X
ABCC7 p.Ser489* 11823525:43:24
status: NEW
view ABCC7 p.Ser489* details
 Mice homozygous for the S489X (B6.129P2-Cftrtm1Unc ) mutation of the CFTR gene, congenic (n ϭ 10 generations) onto C57BL/6J background, (18) and their normal littermates, designated as CFTR-/- and CFTRϩ/ϩ , respectively, were bred in our Animal Core facility. Login to comment