ABCMdb

PMID: 11773614

Kunzelmann K, Mall M
Electrolyte transport in the mammalian colon: mechanisms and implications for disease.
Physiol Rev. 2002 Jan;82(1):245-89., [PubMed]

Sentences

No. Mutations Sentence Comment

948 ABCC7 p.Ser108Phe In rectal biopsies from a CF patient compound heterozygous for the CFTR mutations ⌬F508 and S108F, cAMP-dependent stimulation induces an attenuated Cl- secretory response, which is further increased during the plateau phase of the biphasic CCH response. Login to comment 949 ABCC7 p.Ser108Phe This indicates residual CFTR function of the mutant S108F in native tissue. Login to comment 954 ABCC7 p.Ser108Phe In rectal biopsies from a CF patient compound heterozygous for the CFTR mutations ⌬F508 and S108F, cAMP-dependent stimulation induces an attenuated Cl-secretory response, which is further increased during the plateau phase of the biphasic CCH response. Login to comment 955 ABCC7 p.Ser108Phe This indicates residual CFTR function of the mutant S108F in native tissue. Login to comment