PMID: 11557126

Leslie EM, Deeley RG, Cole SP
Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters.
Toxicology. 2001 Oct 5;167(1):3-23., [PubMed]
Sentences
No. Mutations Sentence Comment
36 ABCC1 p.Glu1089Gln
X
ABCC1 p.Glu1089Gln 11557126:36:23
status: NEW
view ABCC1 p.Glu1089Gln details
 Thus substitution of a glutamate at position 1089 with glutamine as found in the murine protein results in a marked decrease in anthracycline resistance, while transport of LTC4 and E217bG remain unchanged (Zhang et al., 2001). Login to comment