PMID: 11328826

Fitzgerald ML, Mendez AJ, Moore KJ, Andersson LP, Panjeton HA, Freeman MW
ATP-binding cassette transporter A1 contains an NH2-terminal signal anchor sequence that translocates the protein's first hydrophilic domain to the exoplasmic space.
J Biol Chem. 2001 May 4;276(18):15137-45., [PubMed]
Sentences
No. Mutations Sentence Comment
46 ABCA1 p.Ile883Met
X
ABCA1 p.Ile883Met 11328826:46:255
status: NEW
view ABCA1 p.Ile883Met details
 The resulting clones were sequenced in their entirety on both strands and found to be identical to previously published wild type human cDNA sequences except at four codons that have been reported to represent common human polymorphisms (G for A at 2649 (Met for Ile at amino acid 883), T for C at 4943 (Leu for Pro at amino acid 1648), A for G at 5921 (Lys for Arg at amino acid 1974), T for C at 6503 (Leu for Pro at amino acid 2168) (12, 22, 23). Login to comment