PMID: 10962016

Ribalet B, John SA, Weiss JN
Regulation of cloned ATP-sensitive K channels by phosphorylation, MgADP, and phosphatidylinositol bisphosphate (PIP(2)): a study of channel rundown and reactivation.
J Gen Physiol. 2000 Sep;116(3):391-410., [PubMed]
Sentences
No. Mutations Sentence Comment
361 ABCC8 p.Lys1384Met
X
ABCC8 p.Lys1384Met 10962016:361:138
status: NEW
view ABCC8 p.Lys1384Met details
 The hypothesis that phosphorylation of SUR1 favors binding of MgADP and thus functional coupling is supported by the observation that the K1384M mutation in SUR1`s second NBF completely suppress MgADP-dependent reactivation of ATP-inhibited channels (Gribble et al., 1997). Login to comment