PMID: 10933904

Zeitlin PL
Cystic fibrosis gene therapy trials and tribulations.
Mol Ther. 2000 Jan;1(1):5-6., [PubMed]
Sentences
No. Mutations Sentence Comment
20 ABCC7 p.Trp1282*
X
ABCC7 p.Trp1282* 10933904:20:96
status: NEW
view ABCC7 p.Trp1282* details
 Pharmacologic correction of premature-translation termination stop codon mutants in CFTR (e.g., W1282X) by topical treatment with aminoglycosides to promote readthrough to a full-length CFTR has been reported to accomplish a change of 0 to -10 mV (8). Login to comment