PMID: 10926557

Larson JE, Delcarpio JB, Farberman MM, Morrow SL, Cohen JC
CFTR modulates lung secretory cell proliferation and differentiation.
Am J Physiol Lung Cell Mol Physiol. 2000 Aug;279(2):L333-41., [PubMed]
Sentences
No. Mutations Sentence Comment
54 ABCC7 p.Ser489*
X
ABCC7 p.Ser489* 10926557:54:31
status: NEW
view ABCC7 p.Ser489* details
 METHODS Colony Maintenance The S489X cftr-mutant UNC mouse strain was obtained from Jackson Laboratories as a fifth-generation backcross. Login to comment 57 ABCC7 p.Ser489*
X
ABCC7 p.Ser489* 10926557:57:28
status: NEW
view ABCC7 p.Ser489* details
 Under these conditions, the S489X cftr-mutant mice develop intestinal obstruction, and Ͻ5% survive into adulthood. Login to comment 72 ABCC7 p.Ser489*
X
ABCC7 p.Ser489* 10926557:72:32
status: NEW
view ABCC7 p.Ser489* details
 Wild-type CFTR and the knockout S489X allele were amplified in parallel reactions with conditions provided by Jackson Laboratories. Login to comment