PMID: 10898518

Kunzelmann K, Schreiber R, Nitschke R, Mall M
Control of epithelial Na+ conductance by the cystic fibrosis transmembrane conductance regulator.
Pflugers Arch. 2000 Jun;440(2):193-201., [PubMed]
Sentences
No. Mutations Sentence Comment
78 ABCC7 p.Gly551Asp
X
ABCC7 p.Gly551Asp 10898518:78:64
status: NEW
view ABCC7 p.Gly551Asp details
 ENaC is not inhibited by mutant CFTR, e.g. ∆F508-CFTR or G551D-CFTR, suggesting that the enhanced Na+ conductance in CF is caused by a lack of downregulation of ENaC by defective CFTR. Login to comment 114 ABCC7 p.Gly551Asp
X
ABCC7 p.Gly551Asp 10898518:114:48
status: NEW
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 We found that wtCFTR and the common CFTR mutant G551D, but not the most frequent CFTR mutant ∆F508, accumulate in the cell membrane of Xenopus oocytes during cAMP-dependent stimulation (Fig. 3). Login to comment 147 ABCC7 p.Gly551Asp
X
ABCC7 p.Gly551Asp 10898518:147:140
status: NEW
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 Summary of fluorescence measurements using confocal microscopy images of cell membranes of oocytes expressing wtCFTR, ∆F508-CFTR and G551D-CFTR as well as water-injected control oocytes. Login to comment 190 ABCC7 p.Arg1066Cys
X
ABCC7 p.Arg1066Cys 10898518:190:27
status: NEW
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ABCC7 p.Cys225Arg
X
ABCC7 p.Cys225Arg 10898518:190:12
status: NEW
view ABCC7 p.Cys225Arg details
 Analysis of C225R-CFTR and R1066C-CFTR. Login to comment