PMID: 10704942

Abrahem A, Certad G, Pan X, Georges E
Pleiotropic resistance to diverse antimalarials in actinomycin D-resistant Plasmodium falciparum.
Biochem Pharmacol. 2000 May 1;59(9):1123-32., [PubMed]
Sentences
No. Mutations Sentence Comment
185 ABCC1 p.Ser1034Cys
X
ABCC1 p.Ser1034Cys 10704942:185:167
status: NEW
view ABCC1 p.Ser1034Cys details
 Although these results point to the lack of involvement of Pfmdr1 in actD resistance, earlier reports have suggested that several point mutations in Pfmdr1 (Asn86Tyr, Ser1034Cys, Asn1042Asp, and Asp1246Tyr) may be important to chloroquine or mefloquine resistance [38]. Login to comment