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PMID: 10195430
Edelmann HM, Duchek P, Rosenthal FE, Foger N, Glackin C, Kane SE, Kuchler K
Cmdr1, a chicken P-glycoprotein, confers multidrug resistance and interacts with estradiol.
Biol Chem. 1999 Feb;380(2):231-41.,
[PubMed]
Sentences
No.
Mutations
Sentence
Comment
58
ABCB1 p.Ala220Gly
X
ABCB1 p.Ala220Gly 10195430:58:25
status:
NEW
view ABCB1 p.Ala220Gly details
These were due to A118G,
A220G
and T322C nucleotide exchanges, leading to the amino acid changes Lys40Glu in the N-terminal cytoplasmic tail, Thr74Ala in the first transmembrane helix, and Ser108Pro in the first extracellular loop, respectively.
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